The recording for the AHRQ Evidence-based Practice Center (EPC) Program Grand Rounds on pain management is now available. The webinar on November 30 highlighted three recently published EPC reports:

• Acute Treatments for Episodic Migraine
• Nonopioid Pharmacologic Treatments for Chronic Pain
• Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain

The webinar, the third in a series of EPC Grand Rounds, was intended to expand awareness while addressing evidence gaps and implications for clinical practice. Individuals with acute and chronic pain often receive treatment that does not successfully address pain, resulting in profound physical, emotional, and societal costs to them and their families, friends, and caregivers. Centers for Disease Control and Prevention data indicate 50 million adults in the United States have chronic daily pain, with nearly 20 million experiencing high-impact pain that interferes with daily life or work. At the same time, the country is also coping with an opioid and substance use disorders crisis that involves shifting "waves" of overdose deaths associated with heroin, synthetic opioids, and prescription drugs, and intensifying polysubstance use. Clinicians and healthcare systems need more information about multimodal pain care options in outpatient and inpatient settings to effectively treat patients with pain, and people with both pain and either active or historic substance use disorders, including knowledge about complementary care, analgesic medications, and medical devices that are potentially effective.