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Executive Summary – Nov. 16, 2009

Medical Tests - White Paper Series

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These white papers were published in Medical Decision Making and served as background papers for the Methods Guide on Medical Test Reviews.

On May 28-29, 2008, AHRQ hosted a working meeting to discuss particularly challenging methodological issues in assessing medical tests. This working meeting included a group of investigators from the Evidence-based Practice Centers (EPCs), other experts in government, industry, and academia and also marked the launch of a Medical Test Evaluation Work Group within the EPC program. This Work Group was charged with developing guidance for conducting comparative effectiveness reviews of medical test technologies for the AHRQ Effective Health Care Program. A series of scientific publications (white papers) were commissioned for the meeting. These white papers have been published in Medical Decision Making and were intended to serve as background papers for the Work Group, which is expected to complete their draft guidance in the first part of 2010.

Proposals for a Phased Evaluation of Medical Tests. Jeroen G. Lijmer, Mariska Leeflang, Patrick M. M. Bossuyt. AHRQ Manuscript: Published November 9, 2009. Select for HTML or PDF File (118 kb). PDF Help.
Other publication(s): Lijmer, J.G., Leeflang, M., Bossuyt, P.M.M. Proposals for a Phased Evaluation of Medical Tests.Exit Disclaimer Med Decision Making 2009; 29: E13-E21.

Additional Patient Outcomes and Pathways in Evaluations of Testing. Patrick M.M. Bossuyt, Kirsten McCaffery. AHRQ Manuscript: Published November 9, 2009. Select for HTML or PDF File (221 kb). PDF Help.
Other publication(s): Bossuyt, P.M.M., McCaffery, K. Additional Patient Outcomes and Pathways in Evaluations of Testing.Exit Disclaimer Medical Decision Making 2009 ; 29: E30-E38.

Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation. Sarah J Lord, Les Irwig, Patrick MM Bossuyt. AHRQ Manuscript Published November 9, 2009. Select for HTML or PDF File (221 kb). PDF Help.
Other publication(s): Lord, S.J., Irwig, L., Bossuyt, P.M.M. Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation.Exit Disclaimer Medical Decision Making 2009; 29: E1-E5.

Decision-Analytic Modeling to Evaluate Benefits and Harms of Medical Tests – Uses and Limitations. Thomas A. Trikalinos, Uwe Siebert, Joseph Lau. AHRQ Manuscript Published November 9, 2009. Select for HTML or PDF File (114 kb). PDF Help.
Other publication(s): Trikalinos, T.A., Siebert, U., Lau, J. Decision-Analytic Modeling to Evaluate Benefits and Harms of Medical Tests: Uses and Limitations.Exit Disclaimer Medical Decision Making 2009; 29: E22-E29.

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