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what is the best way to deal with a varity of addictions including methamphetamine, nicotine and alcohol.

Can use of visualization help people who feel cold all the time, like some older people who wear long sleeves and sweaters in 88 degree weather and still feel cold. these are people who have been scre...

What is the difference in patient engagement and clinical outcomes of using a health IT system that is designed around the patient vs just the provider - IE a shared care plan like Group Health Coo-op...

For patients with burns of intermediate or indeterminate depth, what is the comparative effectiveness of an assessment method incorporating the moorLDI laser Doppler burns imaging system versus standa...

I have been treated for gout in urgent care /er situations many times. Depending on the provider, the treatment was drastically different. The results were drastically different as well. I will explai...

Suggestion do research on effectiveness of Mental Health Centers, Mental Health Hospitals, Government ran programs on Mental Health Recovery, such as The Wellness Center located in Stockton, the Menta...

Building on the June 2009 AHRQ Evidence Report entitled “Outcomes of Community Health Worker Interventions,” we propose the following new research to generate evidence on: (1) What is the effective...

Can a person get a discount n health isurance for being and staying healthy?

For patients with classical Hodgkin lymphoma (cHL), what is the comparative effectiveness of standard chemotherapy versus inhibitors of activated signaling pathways (such as Jak-STAT)?

What is the effectiveness of physical therapy for the treatment of acute ambulatory and shoulder, hand, and finger injuries following an accident and/or surgery? (Question 1) How do various physica...

COPD guidelines use of therapy CPAP Bi-PAP Drugs? Genetic causes for Anemia where the body does not manufacture or uptake iron reaadily when injected?

For 50 to 70 year old patients with low bone density, what is the comparative effectiveness of 6 Licensed Physical Therapist specified protocol (measured load bearing techniques and specific gait/bala...

In patients with anxiety disorders, what is the effectiveness of using a somatic based therapy (touch) along with the traditional means (talk therapy alone) in treatment? I provide Somatic-based Body...

For patients undergoing total knee replacement surgical procedures, what is the comparative effectiveness of a continuous peripheral nerve block versus intravenous or oral drug therapy to treat postop...

I've been in an auto accident 18 years ago. and I'm a male suffering with osteoporosis what if any clinical studies out there if any in my area of Yorba Linda, California

Are mental health treatment more effective when separate or when integrated into treatment of physical health?

For asthmatic and asthma-prone children, what is the comparative effectiveness of treating with allergen-specific immunotherapy plus standard vs. standard alone?

Evaluation of the effectiveness and quality of patient care using an electronic health record system (EHR).

For adults and children with asthma what is the effectiveness of the Buteyko Breathing method on reducing bronchodilator and inhaled steroid use and improving health status?

For anti-cancer drugs, what is the health outcome benefit of a drug that improves progression free survival without an overall survival benefit and without a documented quality of life benefit?

What is the best second drug choice for treatment of type 2 diabetes?

For adopted and foster children, what is the effectiveness of training adoptive and foster parents in attunement parenting in reducing problem behaviors?

For children experiencing parental divorce, what is the effectiveness of mental health assistance or other outreach for the whole family, for example Kids Turn, versus no intervention. Moreover, conti...

What are the minimum requirements for an EHR to be considered clinically and operationally effective from a compliance and interdisciplinary care management standpoint in Skilled Nursing Facility

Care of the elderly in a home like setting vs an instutional nursing home.

What is the Definition of Human Health? That is the Question.

How do normal weight adults, including those who have always been normal weight and those who have had successful long-term weight loss, succeed in weight management in the face of a work, leisure, an...

prostate,colorectal,and lung cancer screening for nursing home residents---does it have any validity

Will education on a structured eating program decrease obesity in children and adolescents?

Compare the effectiveness of preventive health clinics vs. usual care in promoting systematic preventive health screening.

What evidence exists for programs to increase patient adherence to prescription medications? Which programs/approaches are most effective at increasing adherence for which populations and conditions?...

For people of color with Type 2 Diabetes, what is the most effective way to control blood glucose levels, comparing time released medication such as Lantus with short term effect medication like Novol...

Treatment Resistant Depression

For childbearing women, including those on Medicaid, will independent, woman-centered 'boutique' birthing centers on the midwifery model, with provider-consistent prenatal, birth, lying-in, and early...

TeleHealth Evaluation - To provide a study in using Mobile / Wireless technology connected to Off the Shelf Medical devices in order to store patient readings in common Electronic Health Records (Micr...

for the new treatment for aids and cancer and genetic diseases

Patients are notoriously nonadherent to suggestions for lifestyle change made by their physicians, e.g., weight reduction, increase in exercise, smoking cessation. What evidence exists that a graphic ...

morgellons disease, when will there be a treament availbe for people to use to combat this disease?

For patients with terminal cancer what is the most appropriate paliative treatemt regarding pain control and hydration? Does non traditional medicine as accupuncture herbal remedies faith healing etc...

What evidence exists to support interventions to increase medications adherence of prescription medications by low-income and vulnerable populations? What are the behavioral factors, in addition to ac...

For adult female patients, what is the comparative effective of non-surgical and surgical treatment of chronic pelvic pain?

Alzheimer's Drugs to treat Migraines

For patients - including both children and adult subgroup comparisons - with type 1 diabetes, what is the comparitive differences in HbA1c levels when comparing various treatment options including mul...

What are the comparative treatments including pharmacology, minimally invasive procedures and surgical treatments for women with uterine fibroids? What are the comparative benefits and harms for the ...

What is the comparative effectiveness of using conscious sedation (e.g. a benzodiazepine plus and opioid) vs. anesthesia (e.g., propfol) for performing colonoscopies? What are the advantages and disa...

The key questions for this report focus on the relationship between adherence to treatment and outcomes of treatment, predictors of poor treatment response, and appropriate treatment intervals based o...

For patients with chronic illness (diabetes, asthma, etc), what is the comparative effectiveness of interventions to address concomitant mental health issues on the outcomes of the primary chronic ill...

With the rates of birth by cesarean section on the rise, what factors influence (and which have the greatest impact on) the probability of delivery by cesarean in low-risk women? Which interventions a...

does use of generic medications for seizures result in poorer control (more ER visits and or hospitalizations than the use of brand name medications.

Why do clinical studies for Pharmaceutical treatments differer from real life results using the same treatments? Please compare Pharmaceutical treatments outcomes in real life settings with Pharmaceut...

1. What is the comparative effectiveness of different hormone therapy preparations when used by postmenopausal women or women in the menopausal transition stage for reducing symptoms of menopause: hot...

Key Questions For patients with stable angina (stable coronary artery disease, chronic angina), 1. what is the comparative effectiveness of percutaneous coronary intervention (PCI) plus optimal me...

For low-risk women delivering a full-term baby vaginally, what is the comparative effectiveness of the use of nitrous oxide for pain management versus an epidural or other pain management strategies. ...

Compared to traditional care approaches; how does doctor outreach, education, and support via internet networking technologies (such as Facebook, Twitter, and email) affect outcomes such as adherence ...

they run too many xrays and no MRI

For patients with PKU, there is now a pharmaceutical drug to treat this condition. In the past is was treated by medical foods that eliminated the harmful substance phenylalanine. The cost of the new...

What is the comparative effectiveness of training interdisciplinary healthcare personnel in a virtual, 3D, world versus a physical simulation laboratory? Is training in a virtual, 3D, world transferr...

For infants with exposure to general anesthesia who may have long term adverse neurodevelopmental outcome, what is the effectiveness of an alternate anesthetic technique of regional anesthesia?

What are the Complementary and Alternative Medicine (CAM) treaments (supplements, including herbal formulations) that are helpful in reducing PSA levels associated with begnign prostatic hyperplasia (...

Migraine patients in the ER receive various IV medications from different ER doctors within the physician group. As I have watched particular drug combinations given to my patients and to my daughter ...

For patients with allergic disease, what is the comparative effectiveness of improving health outcomes and lowering healthcare utilization by treating their disease with sublingual immunotherapy (alle...

For newly diagnosed patients with open-angle glaucoma, what is the comparative effectiveness of medication versus laser surgery in controlling 24-hour intraocular pressure?

For children with newly diagnosed epilepsy, ketogenic diet treatment should be evaluated against traditional anti-seizure medication.

Why are there no discussion on comparing the effectiveness of medical foods to phamaceuticals in the treatment of diseases in children? For example the effectiveness of the Ketogenic diet in children ...

Does the implementation of a free standing personal health record for children with special health care needs improve: 1) clinical outcomes, 2)care coordination, 3) communication with providers and de...

All therapy Effectiveness tests need to include compliance verification in order to ensure the validity of the test. For example a test comparing two drugs (in pill form) need to confirm that partici...

1)DVT prophylaxis in special populations. 2)Comparative effectiveness between heparin and LWMH (low molecular weight heparins).

Title: Prevention of venous thromboembolism (VTE) in orthopedic surgery.

Set of related questions for consideration

PICO-Question #1: In patien...

compliance verification for medical devices and medications

For patients with moderate to severe psoriasis, what is the comparative effectiveness of using etanercept (enbrel) versus methotrexate?

What is the comparative effectiveness of interventions for neovascular, age-related macular degeneration(AMD)?

For women, when comparing noninvasive testing,which testing method (echocardiography, MIBI-SPECT, pharmacological testing, etc.) is more accurate in diagnosing coronary artery disease. There has bee...

In the area of autism research, the vast majority of clinical trials conducted to date have addressed only the questions of how an individual treatment compares to a placebo. Extremely few studies ...

For the estimated 70 million Americans with hypertension and the tens of millions more at risk, how would government regulations lowering sodium content in restaurant and processed foods compare to us...

Comparative Effectiveness of Hydroxymethyl-glutaryl-coenzyme A-reductase (HMG CoA) Inhibitors in the Prevention of Neurodegenerative Disease, Septicemia, and Ventilator-associated Pneumonia

The comparative effectiveness of vasopressors, inotropes, and volume in the management of septicemia with hypotension. Population: patients with septicemia and hypotension Intervention/Comparators: ...

Compare the effectiveness of using predictive modeling data vs. traditional care management systems to empower patients that need care after hospital discharge with information.

For the elderly taking cardiovasculare medications, what are the comparative risks and benefits of commonly used herbal supplements.

What is the effectivenis of alternative therapy vs regular medications in reducing cholesterol?

Why are there no comparison contrast studies for MHSAS Consumer Run Programs (such as PACT) against a MHSAS system run (PACT team) for outcomes and cost effectiveness? The expense of using only medica...

for patients with diabetes mellitus,What is the effect of taking the opinion of psychatrist

For children with speech disorder, what is the comparative effectiveness of speech therapy delievered through school based speech pathologist vs outpatient.

What is the comparative effectiveness of primary care provided by independent family nurse practitioners when compared to family practice physicians when the two provider types have similar authority ...

Do patients with small (<1.0 cm) invasive breast cancers need to undergo radiation therapy and/or chemotherapy?

For, the disadvantage, elderly, females, minorities and those of varying alien status, the issue is what health services are available and promoted by health care providers in southern California, and...

For patients with Crohn's disease, what treatments or therapies, alone or in conjunction with one another, provide the highest rate of disease management with the lowest risk of long term complication...

For all patients, addressing continuum of care, has research analysis been performed to promote the benefit of certified nurse case managers working with physicians to promote appropriate utilization ...

What is the percentage of patients with severe anemia undergoing iron infusion therapy, at risk for developing dental problems?

What impacts may the use of EHR have in primary care; how can the benefits be maximized, the costs limited, and the harms minimized?

Does diagnosis, prevention, and treatment of dental caries in children/adolescents affect physical health including septicemia, bone infections, pain, headaches, nutritional diseases, and respiratory ...

What are effective methods for prevention and early detection of skin cancers among Caucasians, African-Americans, and Hispanics? How can new cancerous tumors on the skin be effectively diagnosed in ...

Population: Children < 18 years of age: 1. What are the incidences and prevalences of non-inflammatory pain syndromes (e.g., benign hypermobility syndrome, patellofemoral stress syndrome, fibromyal...