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Department of Health and Human Services

Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.


Apr. 3, 2014

When should adults get ACL repair surgery? Orthopedic surgeons tend to be biased toward surgery and recommend it soon after injury even when studies show it may not benefit the patient.

Apr. 2, 2014

acid reflux / conteneous Burps

Feb. 27, 2014

The relationship and correlation to ADD/ADHD in children to children's sleep apnea

Feb. 27, 2014

PICO: Population(s): Hospitalized patients > 28 days to 21 years of age Intervention(s): Isotonic (0.9% sodium chloride, 154 mEq/L) verses hypotonic maintenance parenteral fluids Comparator(s): Dev ...

Feb. 15, 2014

How the baseline level of BGL and /or HbA1 is correlated with the effectiveness of existing diabetis II terapies.

Feb. 12, 2014

Mini Aspirin in cold weather

Jan. 30, 2014

Macular degeneration

Jan. 28, 2014

Does the implantation of the Argus II Retinal Device System improve the performance of the activities of daily living in patients with sever retinitis pigmentosa?

Jan. 17, 2014

Effects of shade on room light melatonin suppression?

Jan. 9, 2014

Your article on Chronic Pelvic Pain is outdated, simplistic, and totally excludes males who have pelvic pain also.

Dec. 20, 2013

Build more MOBILE UNITS to test people in there NEIGHOODS

Dec. 3, 2013

Environmental Monitoring in Healthcare to Ensure Adequacy of Housekeeping Cleaning and Reduce the Spread of Hospital Acquired Infections (HAIs)

Nov. 20, 2013

As you know marrow transplantation is recomanded in DOCK8 deficiency because this disease is worsening with age and always led to death in the second decad of age, but theses recommandations are bas ...

Nov. 19, 2013

For adult patients (especially the elderly) with non-melanoma skin cancers, what are the compartive risks and benefits of treatment with surgery versus treatment with radiation (either external beam o ...

Nov. 14, 2013

PICO #1 Population(s): Children with infantile hemangiomas (IHs) Intervention(s): Early referral Comparator(s): Delayed referral Outcomes(s): Minimization of functional impairment and/or cosmetic ...

View Topic Suggestion Disposition (PDF) 1.2 MB

Oct. 31, 2013

Treatment of Clostridium difficile infection with fecal transplant therapy in light of the many publications on the topic since the most recent report on C diff was published. This is the most famous ...

Oct. 31, 2013

What interventions are successful in preventing postop infections in vitrectomies on patients with multiple comorbidities. How many and what comorbidities put patients at a higher risk for infection.

View Topic Suggestion Disposition (PDF) 1.2 MB

Oct. 31, 2013

Topic Nomination: Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia 1.Questions to Consider 1. What is the comparative efficacy and effectiveness of currently available ...

Oct. 31, 2013

• What is the optimal antimicrobial prophylaxis regimen for urologic procedures, as categorized by type of procedure: removal of external urinary catheter; cystography, urodynamic study or simple cyst ...

Oct. 24, 2013

RENAL MASS AND LOCALIZED RENAL CANCER *the following questions are recommended to address the healthcare tests and/or treatments this program should consider: • What indicators can be used to predi ...

Sept. 9, 2013

The use of a low dosage of methadone to relieve Restless Leg Syndrome (RLS).

Aug. 19, 2013

I am a 58 year old women treating HVC for 14 years with Peg-Intron and Ribavirin. No one has thought of sharing a coke straw as a way of transmitting the disease. Open membranes and blood to blood.

Aug. 14, 2013

Topic: Prevention of Obstetrical Brachial Plexus Injuries. Babies are injured during birth- some will recovery , others have lifelong disabilities with Erb's Palsy, requiring therapy and surgeries to ...

July 28, 2013

Does short term PPI use cause food/drug allergies or intolerance?

July 18, 2013

For adult patients with rheumatological disorders taking corticosteroids, what are the risks of permanent connective tissue damage causing pain and further disability when fluoroquinolone antibiotics ...

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