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Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients with Cystic Fibrosis

Slide: 16 of 37

rhGH Effects on Intermediate Outcomes in Controlled Trials: Pulmonary Function

This slide presents the summary effects from trials that examined pulmonary function measurements. Pulmonary function measurements showed greater improvement in treated patients than in controls at the conclusion of the studies. However, although the point estimate for percent predicted FEV1 was slightly improved, the difference between treated patients and controls did not reach statistical significance.

The summary effect/mean difference presents the change from baseline as the difference between the means for treated patients and untreated controls.