Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients with Cystic Fibrosis
Summary of Benefits (1)
Potential benefits of rhGH treatment to patients with CF include a reduced hospitalization rate, at 1.6 fewer per year, a conclusion supported by moderate-strength evidence. Weight is associated with mortality risk, and modest gains in weight were observed with treatment (with moderate strength of evidence), but there is no direct evidence about how these gains may modify risk.
Keywords: hospitalization | weight | cystic fibrosis | CF | rhGH | recombinant human growth hormone | human growth hormone | HGH
- Phung OJ, Coleman CI, Baker EL, et al. Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients With Cystic Fibrosis. AHRQ Comparative Effectiveness Review No. 23 (Prepared by University of Connecticut-Hartford Hospital Evidence-based Practice Center under Contract No. 290-2007-10067-I). Rockville, MD: Agency for Healthcare Research and Quality; October 2010. AHRQ Publication No. 11-EHC003-EF.
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