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Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults

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Outline of Material

The material in this presentation covers the results and conclusions from a systematic comparative effectiveness review (CER) titled Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults. The presentation begins with an introduction to treatment-resistant depression (TRD) and the available nonpharmacologic treatment interventions. It also covers: methods used to plan and execute the systematic review, clinically important questions the review sought to answer, results of the review, evidence-based conclusions about effectiveness and harms of treatment interventions, gaps in knowledge, and future research needs uncovered by the systematic review.