Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults
Background: Commonly Reported Adverse Effects and Contraindications
Note: The generally reported information summarized in this slide was not critically reviewed and does not represent findings of the CER. ECT, rTMS, and VNS each have associated potential adverse effects and contraindications, detailed in this table. Psychotherapies, not included in this table, have no commonly reported serious risks or associated adverse events, though they should not be used in patients with cognitive disorders.
- Gaynes BN, Lux L, Lloyd S, et al. Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults. Comparative Effectiveness Review No. 33 (Prepared by RTI International–University of North Carolina (RTI-UNC) Evidence-based Practice Center under Contract No. 290-02-0016-I). Rockville, MD: Agency for Healthcare Research and Quality; September 2011. AHRQ Publication No. 11-EHC056-EF. Available at: http://www.effectivehealthcare.ahrq.gov/trd.cfm.
- Lisanby SH. Electroconvulsive therapy for depression. N Engl J Med 2007 Nov 8;357(19):1939-45. PMID: 17989386.
- Neuronetics NeuroStar TMS SystemTM User Manual. 2006. Available at: http://www.fda.gov/ohrms/DOCKETS/ac/07/briefing/2007-4273b1_15-NeuroStarUserManualRevision.pdf. Accessed November 16, 2011.
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