First- and Second-Generation Antipsychotics for Children and Young Adults
Summary of Comparative Effectiveness Results (2 of 2)
In within-class comparisons of second-generation antipsychotics with each other for pediatric use, olanzapine is not statistically different from risperidone or clozapine for treating schizophrenia, as assessed by clinical global impressions and positive and negative symptoms. The strength of evidence in support of this finding is low.
- Seida J, Schouten J, Mousavi S, et al. First- and Second-Generation Antipsychotics for Children and Young Adults. Comparative Effectiveness Review No. 39 (Prepared by the University of Alberta Evidence-based Practice Center under Contract No. 290-2007-10021). Rockville, MD: Agency for Healthcare Research and Quality; February 2012. AHRQ Publication No. 11(12)-EHC077-EF. Available at www.effectivehealthcare.ahrq.gov/pedantipsych.cfm.
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