First- and Second-Generation Antipsychotics for Children and Young Adults
Adverse Effects of Antipsychotics In Children
Adverse events were examined across all indications in total: adverse events are not expected to be dependent on diagnosis. Several adverse events of interest had no data reported. The analysis focused on key adverse event categories reported in at least one study:
- Weight and body composition
- Blood lipids
- Blood glucose, insulin, and diabetes
- Neuromotor effects (e.g., extrapyramidal symptoms, akathisia, tardive dyskinesia)
- Prolactin and related sexual adverse effects
- Sedative effects
- Seida J, Schouten J, Mousavi S, et al. First- and Second-Generation Antipsychotics for Children and Young Adults. Comparative Effectiveness Review No. 39 (Prepared by the University of Alberta Evidence-based Practice Center under Contract No. 290-2007-10021). Rockville, MD: Agency for Healthcare Research and Quality; February 2012. AHRQ Publication No. 11(12)-EHC077-EF. Available at www.effectivehealthcare.ahrq.gov/pedantipsych.cfm.
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