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Venous Thromboembolism Prophylaxis in Orthopedic Surgery

Slide: 18 of 30

Comparative Effectiveness of Pharmacological Prophylaxis Agents: UFH Versus Desirudin

The relative risk for DVT events is higher for injectable UFH versus desirudin [RR 2.31 (95% CI 1.34 to 4.00)].

  • The relative risk for DVT events is higher for injectable UFH versus desirudin in THR surgery.

The odds for proximal DVT events is higher for injectable UFH versus desirudin [OR 4.74 (95% CI 2.99 to 7.49)].

  • The odds for proximal DVT events is higher for injectable UFH versus desirudin in THR surgery.

Abbreviations: 95% CI = 95-percent confidence interval; DVT = deep vein thrombosis; OR = odds ratio; RR = relative risk; THR = total hip replacement; UFH = unfractionated heparin