Venous Thromboembolism Prophylaxis in Orthopedic Surgery
Characteristics That May Affect Risk of Venous Thromboembolism: Results
Data were insufficient for all surgical or postsurgical characteristics with the exception of two comparisons—general versus regional anesthesia and cemented versus noncemented arthroplasty—in which there was a low strength of evidence. There was low strength of evidence that patients who had general anesthesia had a higher risk of deep vein thrombosis when compared with regional anesthesia, whereas there was no difference in the risk of proximal or distal deep vein thrombosis when compared with regional anesthesia. Data were insufficient to evaluate the impact on the risk of pulmonary embolism, asymptomatic deep vein thrombosis, symptomatic deep vein thrombosis, major bleeding, and minor bleeding or the comparison of spinal versus regional anesthesia and the risk of deep vein thrombosis. There was also low strength of evidence that patients who had cemented arthroplasty had no difference in the risk of deep vein thrombosis or proximal deep vein thrombosis when compared with noncemented arthroplasty. Data were insufficient to evaluate the impact on pulmonary embolism and on the risk of deep vein thrombosis. Data were insufficient to evaluate all other patient or surgical characteristics.
- Sobieraj DM, Coleman CI, Tongbram V, et al. Venous Thromboembolism in Orthopedic Surgery. Comparative Effectiveness Review No. 49 (Prepared by the University of Connecticut/Hartford Hospital Evidence-based Practice Center under Contract No. 290-2007-10067-I). Rockville, MD: Agency for Healthcare Research and Quality; March 2012. AHRQ Publication No. 12-EHC020-EF. Available at www.effectivehealthcare.ahrq.gov/thrombo.cfm.
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