Skip Navigation
Department of Health and Human Services www.hhs.gov
 
Slide Tray
0 slides

Return to Slide Library

Slides

Add Presentation to Slide Tray Presentation:

Second-Generation Antidepressants for Treating Adult Depression—An Update

Slide: 6 of 28

Background: Treatment for Depression

Pharmacotherapy dominates the medical management of depressive disorders, including first-generation and the more recently developed second-generation antidepressants. First-generation antidepressants include tricyclic antidepressants and monoamine oxidase inhibitors. Second-generation antidepressants dominate the medical management of depressive disorders and include selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin and norepinephrine reuptake inhibitors (SSNRIs), and other drugs with related mechanisms of action that selectively target neurotransmitters. The mechanism of action of most of these agents is poorly understood, but they most likely work through their effects on neurotransmitters such as serotonin, norepinephrine, or dopamine in the central nervous system.