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Insulin Delivery and Glucose Monitoring Methods for Diabetes Mellitus: Comparative Effectiveness

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Insulin Delivery and Glucose Monitoring Methods for Diabetes Mellitus: Comparative Effectiveness

This slide set is based on a comparative effectiveness review (CER) entitled Insulin Delivery and Glucose Monitoring Methods for Diabetes Mellitus: Comparative Effectiveness, Comparative Effectiveness Review No. 57, which was developed in July 2012 by the Johns Hopkins University Evidence-based Practice Center, Baltimore, MD, for the Agency for Healthcare Research and Quality (AHRQ) under Contract No. 290-2007-10061-I and is available online at www.effectivehealthcare.ahrq.gov/glucose.cfm.

CERs are comprehensive systematic reviews of the literature that usually compare two or more types of interventions with usual care for the same disease. For this CER, the existing body of evidence on the relative benefits and adverse effects of currently used modes of intensive insulin therapy (continuous subcutaneous insulin infusion [CSII] vs. multiple daily injections [MDI]) and the modes of blood glucose monitoring (real-time continuous glucose monitoring [rt-CGM] vs. self-monitoring of blood glucose [SMBG]) was reviewed. The literature included in this review was identified in searches for studies in the MEDLINE®, EMBASE®, and Cochrane Central Register of Controlled Trials databases using relevant search terms. Studies in children, adolescents, and adults with either type 1 or type 2 diabetes and in pregnant women with pre-existing diabetes were included. Searches were conducted for studies published through July 2011.