Procalcitonin-Guided Antibiotic Therapy
Outline of Material
The material in this presentation covers the results and conclusions from a systematic comparative effectiveness review entitled Procalcitonin-Guided Antibiotic Therapy. It begins with an introduction to procalcitonin and its role in guiding antibiotic therapy in adults and pediatric patients with suspected local or systemic infections. It also covers methods used to plan and execute the systematic review, clinically important questions the review sought to answer, results of the review, evidence-based conclusions about the effects of using procalcitonin to guide antibiotic therapy in patients with local or systemic infections, gaps in knowledge, and the future research needs uncovered by the systematic review.
- Soni NJ, Samson DJ, Galaydick JL, et al. Procalcitonin-Guided Antibiotic Therapy. Comparative Effectiveness Review No. 78 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-based Practice Center under Contract No. HHSA 290-2007-10058-I). Rockville, MD: Agency for Healthcare Research and Quality; August 2012. AHRQ Publication No. 12-EHC124-EF. Available at www.effectivehealthcare.ahrq.gov/procalcitonin.cfm.
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