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Progestogens for Prevention of Preterm Birth

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Clinically Significant Outcomes of Interest in the Comparative Effectiveness Review (1 of 2)

Maternal and fetal/neonatal outcomes examined in the effectiveness review included complications during pregnancy (e.g., chorioamnionitis, antenatal hospitalizations, intrauterine growth restriction, preterm labor), mode of birth and complications (e.g., cesarean birth, surgical complications), prematurity (measured as gestational age at birth, and including birth weight and fetal and neonatal mortality), and postpartum and neonatal complications (in particular, maternal postpartum hemorrhage and intraventricular hemorrhage). Longer term outcomes include neurodevelopmental characteristics and future reproductive outcomes.