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Progestogens for Prevention of Preterm Birth

Slide: 24 of 29

Summary of Benefits: Effect of Formulation and Route of Administration

All formulations succeeded in reducing the risk for preterm birth, and no formulation was effective at reducing the risk for neonatal mortality. However, the evidence is insufficient to support conclusions about the true effect sizes. It is possible that differences associated with progestogen use arise solely from populations studied or other biases. Head-to-head comparisons are needed to provide sufficient evidence to permit conclusions about the comparative effectiveness of formulations.