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Progestogens for Prevention of Preterm Birth

Slide: 25 of 29

Evidence About the Adverse Effects of Progestogens

Study withdrawals were similar for treated and control groups.

The most common adverse effects were related to route of administration, such as injection site discomfort and vaginal irritation. The evidence is insufficient to understand the short- and long-term maternal and fetal adverse effects—potential adverse events were not uniformly assessed in the clinical literature. There are no registries to accumulate data on rare or long-term adverse effects for either mothers or children.