Progestogens for Prevention of Preterm Birth
The Burden of Preterm Birth
Preterm birth is defined as birth prior to the 37th week of pregnancy. Each year in the United States, 12.5 percent of births (representing more than 475,000 infants) occur preterm.
The risk of complications from preterm birth is related to how early the birth occurs. The morbidity and mortality associated with preterm birth represent untold distress for families, as well as significant costs to patients, health care systems, and payers. The estimated additional cost for neonatal care is $17,300 (2004 dollars) per preterm infant.
- Likis FE, Andrews JC, Woodworth AL, et al. Effectiveness of Progestogens for Prevention of Preterm Birth. Comparative Effectiveness Review No. 74 (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I). Rockville, MD: Agency for Healthcare Research and Quality; September 2012. AHRQ Publication No. 12-EHC105-EF. Available at www.effectivehealthcare.ahrq.gov/pretermbirth.cfm.
- Bailit JG, Votruba ME. Medical cost savings associated with 17 alpha-hydroxyprogesterone caproate. Am J Obstet Gynecol 2007 Mar;196(3):219 e1-7. PMID: 17346527.
- Martin JA, Hamilton BE, Sutton PD, et al. Births: final data for 2005. Natl Vital Stat Rep 2007 Dec 5;56(6):1-103. PMID: 18277471.
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