Progestogens for Prevention of Preterm Birth
Progestogens for Preventing Preterm Birth (1 of 2)
Progesterone is a hormone that inhibits the uterus from contracting. It is involved in maintaining pregnancy, especially early in gestation.
The accumulating clinical evidence showing that progesterone can prolong pregnancy for women at risk of preterm birth has led some organizations to recommend progesterone for pregnant women with prior preterm birth.
“Progestogen” is an inclusive term for substances with biologic activity similar to the endogenous hormone progesterone. Progestogens include natural progesterone, synthetic progesterone, and synthetic progestins that are similar but not identical in chemical structure.
- Likis FE, Andrews JC, Woodworth AL, et al. Effectiveness of Progestogens for Prevention of Preterm Birth. Comparative Effectiveness Review No. 74 (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I). Rockville, MD: Agency for Healthcare Research and Quality; September 2012. AHRQ Publication No. 12-EHC105-EF. Available at www.effectivehealthcare.ahrq.gov/pretermbirth.cfm.
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