Noninvasive Positive-Pressure Ventilation for Acute Respiratory Failure: Comparative Effectiveness
Conclusions (2 of 2)
Direct comparisons of continuous positive airway pressure and bilevel positive airway pressure in patients with acute cardiogenic pulmonary edema showed similar efficacy.
Limited evidence suggested potential benefits of NPPV for patients with acute respiratory failure as a method to facilitate weaning from invasive ventilation or to prevent recurrent postextubation respiratory failure in those at high risk. Limited evidence also indicated that the effects of using NPPV were lower in clinical trials designed to replicate usual clinical practice.
- Williams JW Jr, Cox CE, Hargett CW, et al. Noninvasive Positive-Pressure Ventilation (NPPV) for Acute Respiratory Failure: Comparative Effectiveness. Comparative Effectiveness Review No. 68 (Prepared by the Duke Evidence-based Practice Center under Contract No. 290-2007-10066-I). Rockville, MD: Agency for Healthcare Research and Quality; July 2012. AHRQ Publication No. 12-EHC089-EF. Available at www.effectivehealthcare.ahrq.gov/nppv.cfm.
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