Noninvasive Technologies for Diagnosing Coronary Artery Disease in Women
Background: The Importance of Diagnosing Coronary Artery Disease in Women
Diagnosing coronary artery disease (CAD) is a crucial step toward improving outcomes in women. Overall, up to or as many as 40 percent of initial cardiac events are fatal.
The 2005 American Heart Association update on heart disease and stroke estimated new and recurrent myocardial infarction (MI) to occur in 520,000 men versus 345,000 women; among these, 93,800 men and 85,700 women die annually as the result of an MI. Women who have had an acute MI have a worse prognosis than men, with a greater recurrence of MI and higher mortality.
The goals of a diagnostic workup for women who have symptoms suspicious for CAD are to identify CAD with optimal accuracy and to establish the basis for instituting preventive and therapeutic interventions.
- Dolor RJ, Patel MR, Melloni C, et al. Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women. Comparative Effectiveness Review No. 58 (Prepared by the Duke Evidence-based Practice Center under Contract No. 290-2007-10061-I). Rockville, MD: Agency for Healthcare Research and Quality; June 2012. AHRQ Publication No. 12-EHC034-EF. Available at www.effectivehealthcare.ahrq.gov/diagnosecad.cfm.
- American Heart Association. Heart and Stroke Statistics. 2005 Update. Available at www.americanheart.org.
- Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics—2010 update: a report from the American Heart Association. Circulation 2010;121(7):e46-e215. PMID: 20019324.
- Mieres JH, Shaw LJ, Arai A, et al. Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease: consensus statement from the Cardiac Imaging Committee, Council on Clinical Cardiology, and the Cardiovascular Imaging and Intervention Committee, Council on Cardiovascular Radiology and Intervention, American Heart Association. Circulation 2005;111(5):682-96. PMID: 15687114.
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