Treatment for Hepatitis C Virus Infection in Adults: Comparative Effectiveness
Additional Information: Relevance of the Findings of the CER to Screening for Hepatitis C Virus Infection
The findings of the comparative effectiveness review (CER) are also relevant to recommendations for hepatitis C virus (HCV) screening, which are based in part on the effectiveness of treatments in patients found through screening to have HCV infection. Important new evidence that may affect assessments regarding potential benefits of screening include stronger evidence of the link between achieving a sustained virologic response (SVR) and improvement in clinical outcomes, as well as evidence showing substantially higher SVR rates with newer triple-therapy regimens with boceprevir or telaprevir in patients with HCV genotype 1 infection, the predominant type of HCV infection in the United States.
- Chou R, Hartung D, Rahman B, et al. Treatment for Hepatitis C Virus Infection in Adults: A Comparative Effectiveness Review. Evidence Report No. 76 (Prepared by the Oregon Evidence-based Practice Center under Contract No. 290-2007-10057-I). Rockville, MD: Agency for Healthcare Research and Quality; August 2012. AHRQ Publication No. 12-EHC113-EF. Available at www.effectivehealthcare.ahrq.gov/hepctreatment.cfm.
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