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Drug Therapy for Rheumatoid Arthritis in Adults

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Summary of Studies Included in the Comparative Effectiveness Review

The analysis included 258 published articles reporting on 211 studies:

  • 31 head-to-head randomized controlled trials
  • 1 head-to-head nonrandomized controlled trial
  • 44 placebo-controlled trials
  • 28 meta-analyses or systematic reviews
  • 107 observational studies
  • 30 studies for quantitative synthesis for analysis of effects on disease activity and joint damage
  • 42 studies for quantitative syntheses for analysis of adverse effects