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First- and Second-Generation Antipsychotics for Children and Young Adults

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First- and Second-Generation Antipsychotics for Children and Young Adults

This slide set is based on a comparative effectiveness review (CER 39) First- and Second-Generation Antipsychotics for Children and Young Adults that was developed by the University of Alberta Evidence-based Practice Center for the Agency for Healthcare Research and Quality (AHRQ) under Contract No. 290-2007-10021 and is available online at www.effectivehealthcare.ahrq.gov/pedantipsych.cfm.

CERs are comprehensive systematic reviews of the literature that usually compare two or more types of treatment, such as different drugs or adding a second drug to usual care for the same disease. The literature included in this review was identified in searches for trials and studies that explicitly evaluated first-generation and second-generation antipsychotics in children, adolescents, and young adults ≤24 years of age. Searches were conducted for controlled trials (randomized and nonrandomized) and cohort studies published from January 1987 up to February 2011.