Second-Generation Antidepressants for Treating Adult Depression—An Update
Outcomes of Interest in Studies on Second-Generation Antidepressants for Depression
The health outcomes of interest from the included studies were response, remission, speed of response/remission, relapse, quality of life, functional capacity, and hospitalization. The safety and tolerability of second-generation antidepressants were measured by overall adverse events, withdrawals because of adverse events, serious adverse events, and specific adverse events (hyponatremia, seizures, suicide, hepatotoxicity, weight gain, gastrointestinal symptoms, sexual side effects, and others).
- Gartlehner G, Hansen RA, Morgan LC, et al. Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression: An Update of the 2007 Comparative Effectiveness Review. Comparative Effectiveness Review No. 46 (Prepared by the RTI International–University of North Carolina Evidence-based Practice Center under Contract No. 290-2007-10056-I). Rockville, MD: Agency for Healthcare Research and Quality; December 2011. AHRQ Publication No. 12-EHC012-EF. Available at www.effectivehealthcare.ahrq.gov/secondgenantidep.cfm.
Your slide tray is being processed.