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Second-Generation Antidepressants for Treating Adult Depression—An Update

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Comparative Effectiveness Review on Second-Generation Antidepressants for Adults With Depression

A systematic review of 248 clinical studies published between January 1980 and January 2011 sought to determine the effectiveness, benefits, and adverse effects of second-generation antidepressants for adults with depression. This presentation is provided to assist in decisionmaking and should not be construed to represent clinical recommendations or guidelines. The full report is available at