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Off-Label Use of Atypical Antipsychotics: An Update

Slide: 15 of 47

Summary of Studies Included in the Comparative Effectiveness Review (1 of 2)

Studies of efficacy, effectiveness, benefits, and adverse effects of atypical antipsychotics as treatment for several off-label indications are reported in the clinical literature. There are no reports of studies of off-label use of the newer atypical antipsychotics asenapine, iloperidone, and paliperidone. The atypical antipsychotic clozapine was not included in the review; clozapine can only be prescribed in a system that provides weekly monitoring for bone marrow-suppression disorders as a condition of receiving the treatment.