Off-Label Use of Atypical Antipsychotics: An Update
Introduction to Atypical Antipsychotics (4 of 4)
Recommendations or advertisements that promote the use of pharmaceuticals for indications that have not been approved by the FDA (i.e., off-label) are illegal. Off-label prescribing by physicians is permitted. Given that antipsychotics are used off label, what is known about the efficacy or comparative effectiveness, benefits, and adverse effects of atypical antipsychotics when prescribed for unapproved (off-label) indications?
- Maglione M, Ruelaz Maher A, Hu J, et al. Off-Label Use of Atypical Antipsychotics: An Update. Comparative Effectiveness Review No. 43 (Prepared by the Southern California RAND Evidence-based Practice Center under Contract No. HHSA 290-2007-10062-I). Rockville, MD: Agency for Healthcare Research and Quality; September 2011. AHRQ Publication No. 11(12)-EHC087-EF. Available at www.effectivehealthcare.ahrq.gov/offlabelantipsych.cfm.
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