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Noninvasive Technologies for Diagnosing Coronary Artery Disease in Women

Slide: 18 of 23

Conclusions (1 of 2)

This systematic review has provided evidence for the summary sensitivities and specificities of exercise/stress ECG, exercise/stress ECHO, SPECT, CMR, and coronary CTA compared with coronary angiography in women. Overall, within a given modality, the summary sensitivities and specificities were similar for both types of populations (unknown coronary artery disease [CAD] and mixed known and no known CAD) and for all studies when compared with good-quality studies.

When considering only the good-quality studies, the diagnostic accuracy of detecting CAD in women presenting with anginal chest pain but with no known CAD appeared to be better (in descending order) for coronary CTA, SPECT, ECHO, CMR, and ECG. However, the confidence intervals were wide, especially for CTA and CMR. The strength of evidence for findings related to the diagnostic accuracy of coronary CTA and CMR was rated low and more studies in women would be needed to support the findings.

CMR = cardiac magnetic resonance imaging; CTA = computed tomography angiography; ECG = electrocardiography; ECHO = echocardiography; SPECT = single photon emission computed tomography