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Treatment for Hepatitis C Virus Infection in Adults: Comparative Effectiveness

Slide: 10 of 34

Clinical Questions Addressed by This Comparative Effectiveness Review (2 of 3)

This comparative effectiveness review attempted to address four key questions. Key Question (KQ) 2 is listed on this slide:

KQ 2: This key question has two parts:

a. What is the comparative effectiveness of antiviral treatments on intermediate outcomes, such as the rate of sustained virologic response or histologic changes in the liver?

b. How does the comparative effectiveness of antiviral treatment for intermediate outcomes vary according to patient subgroup characteristics including, but not limited to, HCV genotype, age, race, sex, stage of disease, or genetic markers?