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Drug Therapy for Rheumatoid Arthritis in Adults

Slide: 11 of 45

Clinical Questions Addressed by the Comparative Effectiveness Review

The comparative effectiveness review addressed several key clinical questions, including:

  • Do drug therapies for rheumatoid arthritis (RA) differ in their ability to reduce disease activity, to slow or limit the progression of joint damage, or to maintain remission?
  • Do drug therapies for RA differ in their ability to improve patient-reported symptoms, functional capacity, or quality of life?
  • Do drug therapies for RA differ in harms, tolerability, patient adherence, or adverse effects?
  • What are the comparative benefits and harms of drug therapies for RA in subgroups of patients based on stage of disease, prior therapy, demographics, concomitant therapies, or comorbidities?