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Department of Health and Human Services

Read Suggested Topics for Research

Browse or use the search box below to see suggestions submitted by others. Click on the text link to read the full suggestion. Suggestions are presented as they were submitted and are not edited. See Search for Guides, Reviews, and Reports for research in progress and final reports.

Suggestions that have completed the Program's selection process are identified by a topic suggestion disposition (PDF). Suggestions submitted prior to 2008 were reviewed under a different process and disposition reports may not be available.


July 1, 2010

Annual reviews for states' Medicaid consumer based services on those permanently disabled, without possibility of stem cell transplant, or miracle from "on high" due to age and/or severity is costly, ...

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June 25, 2010

For patients being evaluated for coronary artery disease, what is the comparative effectiveness of strategies using intravascular diagnostic procedures compared to angiography alone or other strategie ...

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View Topic Suggestion Disposition (PDF) 591 kB

View Topic Suggestion Disposition (PDF) 591 kB

June 25, 2010

Comparative effectiveness of treatments for cataract

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June 17, 2010

How to keep the body flexible and in proper alignment to prevent injury and complications after surgery?

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May 25, 2010

For adult chronically-ill patients of low SES who are living in an urban environment, what is the comparative effectiveness of earlier versus later palliative care involvement on quality of life and t ...

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May 20, 2010

Diagnosis and Management Pressure Ulcer The questions we would like answered by this evidence review are the following: 1. How can we identify patients at risk for pressure ulcers in the hospi ...

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View Topic Suggestion Disposition (PDF) 126 kB

View Topic Suggestion Disposition (PDF) 126 kB

May 20, 2010

1. What are the benefits and harms of rhythm control compared to rate control (including newer agents) ? What are the benefits and harms of strict vs more lenient rate control? 2. What are the bene ...

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May 19, 2010


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May 17, 2010

For ST segment elevation patients undergoing PCI -percutaneous coronary intervention, what is the best combination with regard to anticoagulation, device and approach to reduce mortality and length of ...

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May 11, 2010

The Obesity Action Coalition is interested in an investigation of the comparative effectiveness of treatments for obesity including: 1. What is the comparative effectiveness of bariatric surgery (gas ...

View Topic Suggestion Disposition (PDF) 154 kB

May 10, 2010

Question: What is the etiology of cryptorchidism? What are the environmental factors (maternal smoking, maternal diabetes mellitus etc.) that may contribute to the development of this condition? Qu ...

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May 3, 2010

Do "evidence-based" cancer screening recommendations that do not consider racial/ethnic variation in disease patterns contibute to to the more advanced disease stage at diagnosis and higher mortality ...

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May 3, 2010

In terms of fixing depression what is the difference between cognitive behavioral therapy, medication and Subconscious Restructuring® in terms of measurable documented effectiveness?

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Apr. 29, 2010

I want to suggest that people who have the medical aid should use the government hospital. I feel that the government should support its family first before out sourcin. I do not know in other State b ...

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Apr. 22, 2010

Women before 50 with column surgery & without using hormones., osteopenia & scoleosis

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Apr. 21, 2010

There is no standard for care pertaining to chronic wounds and ischemic or diabetic ulcers on the extremities of patients. What is the comparative effectiveness of treating patient’s, including pat ...

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Apr. 19, 2010

For treatment of osteoarthritis, consider a rheumatoid arthritis drug; compare the effectiveness to see if it would work better than the ordinary osteoarthritis drug; since osteoarthritis is similar i ...

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Apr. 19, 2010

For people with seasonal allergies, what are the best treatment options? Please consider effectiveness, ease of use, side effects, cost & effects on pregnancy

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Apr. 14, 2010

Regarding the amount of cardiac rhythm device´s recalls, FDA warning letters to manufactures and Product Performance Report information (based on Advamed guide) available, it would be interesting to d ...

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Apr. 11, 2010

The persistent rate of new HIV infections is the major obstacle to reducing the morbidity and mortality due to HIV in the United States. Screening for HIV in asymptomatic individuals has many potentia ...

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Apr. 9, 2010

Invention and coding of data analysis methods generally useful for making valid claims from large observational data sets.

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Mar. 20, 2010

Is transradial access comparable to transfemoral access with respect to efficacy and superior with respect of safety in primary percutaneous coronary intervention in ST-elevation myocardial infarction ...

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Mar. 19, 2010

Whether Epidural use to contain the labor pay would result in women's memory loss over a longer-term period

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Mar. 9, 2010

Autism Speaks submitted a nomination on treatments for autism spectrum disorders and it was forwarded to an EPC who was refining a related topic nomination. Three primary areas of the Autism Speaks ...

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Feb. 17, 2010

For patients with mobility limitations but who have trunk stability and upper body strength, what is the comparative risk and benefits of adopting a self-managed bedside commode system versus older as ...

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