Skip Navigation
Department of Health and Human Services www.hhs.gov
 
 

Topic Suggestion Description

Date submitted: May 14, 2014

Briefly describe a specific question, or set of related questions, about a health care test or treatment that this program should consider.
We would like to nominate the following topics for the methodological AHRQ reports:
1. Examining the robustness of the using GRADE to classify the evidence as high, moderate, or low.
2. Machine learning methods for screening of the retrieved studies (comparative efficiency of various methods).
3. Machine learning methods for new evidence surveillance.
4. Network meta-analyses of comparative effectiveness and safety with heterogeneity evaluation and ranking the quality of evidence.
5. Methods of imputing missing data in quantitative analyses.
6. Quantification of the value of the information for judging benefits and harms and for determining future research needs.
7. Valid methods for expert consensus development in cases of low or insufficient evidence (e.g. formalization and quantification of Delphi or other consensus approaches).
8. Validating the rapid review vs. systematic review and understanding the level of bias introduced with this alternative methodological approach.

Importance

Describe why this topic is important.
Valid and efficient methodology in the comprehensive evidence-based reports would improve clinical research methodology and inform decision-making in clinical care and improve the quality of healthcare and patient outcomes.

Potential Impact

How will an answer to your research question be used or help inform decisions for you or your group?
Elsevier Clinical Solutions utilize the high quality AHRQ reports and methodological guides to produce better syntheses of research data to inform development of better information resources for those who need them at the point of care.

Nominator Information

Other Information About You: (optional)
Please choose a description that best describes your role or perspective: (you may select more than one category if appropriate)
My goal is development and implementation of EBM standards in Elsevier products, routine monitoring of the compliance with EBM standards and assuring quality in Elsevier print and electronic products.
If you are you making a suggestion on behalf of an organization, please state the name of the organization
The Evidence- Based Medicine Center of Excellence
Please tell us how you heard about the Effective Health Care Program
Elisabeth Kato suggested nominating methodological topics