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What are the risks of taking PPI's (proton pump inhibitors)e.g. Nexium, and Prilosec OTC over a long period of time for chronic heart burn? What does this do to Vitamin B12 and Vitamin D levels in those subjects? Does the chronic use of PPI's increase dep

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Describe your topic.

What are the risks of taking PPI's (proton pump inhibitors) e.g. Nexium, and Prilosec OTC over a long period of time for chronic heart burn? What does this do to Vitamin B12 and Vitamin D levels in those subjects? Does the chronic use of PPI's increase depression like symptoms due to low levels of Vitamin B12 and vitamin D for those taking PPI's for a long period of time?

Describe why this topic is important.

In 2009 these drugs were the third largest class of drugs sold in the country.

Tell us why you are suggesting this topic.

 

Target date.

 

Describe what you are doing currently and what you are hoping will change because of a new evidence report.

 

How will you or your group use the information from a new evidence report?

This information will help drug companies be more proactive in warning people of the adverse side effects. It will also help to increase research on the importance of vitamin B12 and Vitamin D for overall good health.

How would you or your group plan to disseminate information from the report? Who would you plan to disseminate it to?

 

Do you know of organizations that could use an evidence report to change clinical practice? Are you a part of, or have you been in contact with, any organizations that might implement the research findings of an evidence report?

American Medical Association

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Provide a description of your role or perspective

patient

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Page last reviewed January 2018
Page originally created August 2017

Internet Citation: What are the risks of taking PPI's (proton pump inhibitors)e.g. Nexium, and Prilosec OTC over a long period of time for chronic heart burn? What does this do to Vitamin B12 and Vitamin D levels in those subjects? Does the chronic use of PPI's increase dep. Content last reviewed January 2018. Effective Health Care Program, Agency for Healthcare Research and Quality, Rockville, MD.
https://effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-risks-of-taking-ppis

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