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Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer

Systematic Review ARCHIVED May 27, 2010

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Archived: This report has been updated.

Excerpt

This is a comparative effectiveness review of alternative radiation therapy (RT) modalities in the treatment of head and neck cancer including: conventional or two-dimensional (2DRT), three-dimensional conformal (3DCRT), intensity-modulated (IMRT), and proton beam radiotherapy. Key questions that will be addressed are whether any of these modalities is more effective than the others: (1) in reducing normal tissue toxicity and adverse events, and improving quality of life; (2) in improving local tumor control, time to disease progression, and survival; (3) when used in certain anatomic locations or patient subpopulations; and, finally, (4) whether there is more variation in patient outcomes with any modality secondary to user experience, treatment planning, or target volumes.

Project Timeline

Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer

Jan 1, 2005
Topic Initiated
May 27, 2010
Systematic Review Archived
Page last reviewed December 2019
Page originally created November 2017

Internet Citation: Systematic Review: Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer. Content last reviewed December 2019. Effective Health Care Program, Agency for Healthcare Research and Quality, Rockville, MD.
https://effectivehealthcare.ahrq.gov/products/head-neck-cancer/research

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