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Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke

Technical Brief ARCHIVED Jan 18, 2011

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Archived: This report is greater than 3 years old. Findings may be used for research purposes, but should not be considered current.

Excerpt

Acute ischemic strokes are associated with poor outcomes and high healthcare burden. In patients with occlusions of large cerebral vessels, patients with high baseline stroke severity scores as defined by the National Institute of Health Stroke Score (NIHSS), and patients unlikely to benefit or having failed treatment with intravenous (IV) recombinant tissue plasminogen activator (rtPA), there is a need for alternative methods of revascularization which can improve outcomes without increasing the risk for intracranial hemorrhage. The uses of various neurothrombectomy devices (clot retrievers, aspiration/suction devices, snare-like devices, ultrasonography technologies, and lasers) have been examined in these populations. Currently, two neurothrombectomy devices are FDA-cleared through the FDA 510(k) process: the MERCI clot retriever and the Penumbra System. Various ongoing clinical trials are currently evaluating the impact of these devices, as well as other (off-label) neurothrombectomy devices, for the treatment of acute ischemic stroke. The goal of this technical brief is to describe neurothrombectomy devices currently being used or actively investigated in the treatment of patients with acute ischemic stroke and to summarize the evidence supporting their use.

Journal Publications

Baker WL, Colby JA, Tongbram V, et al. Review: Neurothrombectomy Devices for the Treatment of Acute Ischemic Stroke: State of the Evidence. Ann Intern Med 2011 Jan 17. [Epub ahead of print]

Project Timeline

Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke

Feb 17, 2010
Topic Initiated
Feb 19, 2010
Jan 18, 2011
Technical Brief Archived
Page last reviewed December 2019
Page originally created November 2017

Internet Citation: Technical Brief: Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke. Content last reviewed December 2019. Effective Health Care Program, Agency for Healthcare Research and Quality, Rockville, MD.
https://effectivehealthcare.ahrq.gov/products/ischemic-stroke-treatment/technical-brief

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