Chronic pain affects millions of adults in the United States. It is the leading cause of disability and significantly impacts physical and mental functioning and quality of life. Chronic pain is often defined as pain lasting 3 months or longer or persisting past the normal time for tissue healing.
HHS is committed to the promotion of evidence-based approaches to safe and appropriate treatment of chronic pain.
The AHRQ Evidence-based Practice Center Program, on request from the U.S. Centers for Disease Control and Prevention, has conducted a comprehensive synthesis of the recent evidence from the peer-reviewed literature on the effectiveness and harms of noninvasive treatments for chronic noncancer pain. The current state of the science on treatments for the most common types of chronic pain are presented in the following three reports: