1. What is the decision or change (e.g., clinical topic, practice guideline, system design, delivery of care) you are facing or struggling with where a summary of the evidence would be helpful?

I would like to know if colorectal cancer (CRC) screening colonoscopy transmits Parkinson's disease (PD) since it is theoretically conceivable [Viruses. 2021;13(7):1394].

2. Why are you struggling with this issue?

The association between CRC screening colonoscopy and PD does not seem to have been explored.

3. What do you want to see changed? How will you know that your issue is improving or has been addressed?

I would like to know if PD is iatrogenically transmissible. "The implementation of large-scale, systematic studies are necessary in order to adequately assess the potential risks associated with the potential transmission and propagation of misfolded protein in humans."[Biomolecules. 2021;11(2):207]

4. What will you do with the evidence report?

I may undergo a CRC screening colonoscopy if it is proven that iatrogenic transmission of PD pathology is not occurring.

Optional Information About You

What is your role or perspective? Patient

May we contact you if we have questions about your nomination? Yes