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Does short term PPI use cause food/drug allergies or intolerance?

NOMINATED TOPIC | July 28, 2013
Briefly describe a specific question, or set of related questions, about a health care test or treatment that this program should consider.

Does short term PPI use cause food/drug allergies or intolerance?

Describe why this topic is important.

Researchers have speculated that Proton Pump Inhibtors and Gastric acid suppressors may cause allergies, via sensitization against oral proteins and drugs. However, no human study has been performed. It would be a good starter study to look at 1-2 month PPI usage, which is a standard prescription.

How will an answer to your research question be used or help inform decisions for you or your group?

It could help evaluate how long you can safely use PPI's, without developing a lifelong food allergy.

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Page last reviewed November 2017
Page originally created July 2013

Internet Citation: Does short term PPI use cause food/drug allergies or intolerance?. Content last reviewed November 2017. Effective Health Care Program, Agency for Healthcare Research and Quality, Rockville, MD.
https://effectivehealthcare.ahrq.gov/get-involved/nominated-topics/does-short-term-ppi-use-cause-fooddrug-allergies-or-intolerance-2

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