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Many physicians will state "Pulmonary Hypertension" as the nature of a patient's illness with the underlying meaning of "Right-sided Heart involvement". What is the comparative risks associated with the same in clinical trials.

NOMINATED TOPIC | February 8, 2010
Briefly describe a specific question, or set of related questions, about a health care test or treatment that this program should consider.

Many physicians will state "Pulmonary Hypertension" as the nature of a patient's illness with the underlying meaning of "Right-sided Heart involvement". What is the comparative risks associated with the same in clinical trials.

Does your question include a comparison of different health care approaches? (If no, your topic will still be considered.)
If yes, explain the specific technologies, devices, drugs, or interventions you would like to see compared:
What patients or group(s) of patients does your question apply to? (Please include specific details such as age range, gender, coexisting diagnoses, and indications for therapy.)

All age groups.

Are there subgroups of patients that your question might apply to? (For example, an ethnic group, stage or severity of a disease.)
Describe the health-related benefits you are interested in. (For example, improvements in patient symptoms or problems from treatment or diagnosis.)
Describe any health-related risks, side effects, or harms that you are concerned about.

Appropriateness for EHC Program

Does your question include a health care drug, intervention, device, or technology available (or likely to be available) in the U.S.?

no

Which priority area(s) and population(s) does this topic apply to? (check all that apply)
EHC Priority Conditions (updated in 2008)
  • Cardiovascular disease, including stroke and hypertension
AHRQ Priority Populations
None
Federal Health Care Program
None

Importance

Describe why this topic is important.

When creating decision support applications for patients with Heart Failure, the patient's problem when stated simply as "Pulmonary Hypertension" to include underlying meaning of "Right-sided Heart involvement", could generate undesired alerts. Clinicians should explicitly state "Pulmonary Hypertension without right heart involvement". Clinical research articles could make the same mistake.

What specifically motivated you to ask this question? (For example, you are developing a clinical guideline, working with a policy with large uncertainty about the appropriate approach, costly intervention, new research you have read, items in the media you may have seen, a clinical practice dilemma you know of, etc.)

Creating decision support applications for patients with Heart Failure.

Does your question represent uncertainty for clinicians and/or policy-makers? (For example, variations in clinical care, controversy in what constitutes appropriate clinical care, or a policy decision.)

no

If yes, please explain:

Potential Impact

How will an answer to your research question be used or help inform decisions for you or your group?

It will help resolve proper definition of all medical concepts.

Describe the timeframe in which an answer to your question is needed.
Describe any health disparities, inequities, or impact on vulnerable populations your question applies to.

Nominator Information

Other Information About You: (optional)
Please choose a description that best describes your role or perspective: (you may select more than one category if appropriate)

It will help resolve proper definition of all medical concepts.

Are you making a suggestion as an individual or on behalf of an organization?

Individual

Please tell us how you heard about the Effective Health Care Program
Page last reviewed November 2017
Page originally created February 2010

Internet Citation: Many physicians will state "Pulmonary Hypertension" as the nature of a patient's illness with the underlying meaning of "Right-sided Heart involvement". What is the comparative risks associated with the same in clinical trials.. Content last reviewed November 2017. Effective Health Care Program, Agency for Healthcare Research and Quality, Rockville, MD.
https://effectivehealthcare.ahrq.gov/get-involved/nominated-topics/many-physicians-will-state-pulmonary-hypertension-as-the-nature-of-a-patients-illness-with-the-underlying-meaning-of-right-sided-heart-involvement-what-is-the-comparative-risks-associated-with-the-same-in-clinical-trials

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