1. What is the decision or change (e.g., clinical topic, practice guideline, system design, delivery of care) you are facing or struggling with where a summary of the evidence would be helpful?

A 12 or 18 core prostate blind biopsy. One million dangerous prostate blind (TRUS) biopsies are performed in the USA each year and they should be banned: Invasive, dangerous, degrading and unnecessary. Men with a high PSA tests result are often sent to an urologist for a blind biopsy. You may not own your biopsy samples. Blind prostate biopsy cost in the USA is at least $3 billion annually. False positives and false negatives do occur. Men should be told about other options; Percent free PSA test, 4Kscore test, SelectMDX, PCA3 test or a 3T MRI test before receiving a blind biopsy. These tests can often eliminate the need for a risky and invasive blind biopsy. Unfortunately, sometimes insurance companies may not pay for other tests. Insertion of 12 or 18 large hollow needles through the dirty rectum into a gland the size of a walnut, a blind biopsy can result in pain, infections, a risk of temporary or permanent erectile dysfunction https://www.youtube.com/watch?v=IRbJPOgIU0k. Biopsies can cause, urinary problems, An infection rate of 7.2%, up to a 6.9% hospitalization rate within 30 days from a complication, sometimes even death from sepsis (About 1.3 to 3.5 deaths per 1,000). There is also debate that a biopsy may spread cancer because of needle tracking. A blind biopsy is degrading and can also increase PSA reading for several weeks or months, further frightening men into unnecessary treatment. Blind biopsies are almost never performed on other organs.