Substance Use Disorders in Adolescents Questions: What are efficacious/effective interventions for substance use disorders occurring in adolescents (generally and by specific substance of abuse excluding tobacco). Alcoholics Anonymous/Narcotics Anonymous/12-step interventions Behavioral interventions including CBT, Family therapies Pharmacologic interventions How do these interventions compare with each other Populations: By age younger and older adolescents Gender, ethnic, and racial diferences Comorbid diagnoses : depression and other mood disorders, anxiety disorders, disruptive behavior disorders and ADHD Harms: Worsening of use Diversion/abuse of medication

Describe why this topic is important. Significant prevalence of SUDs in adolescents New findings from the nationally representative samples of US youth reveal that the lifetime prevalence of alcohol use disorders is approximately 8 % and illicit drug use disorders is 2-3 % (Merikangas et al. in J Am Acad Child Adolesc Psychiatry 49(10):980-989, 2010; Swendsen et al. in Arch Gen Psychiatry 69(4):390-398, 2012; SAMHSA in Results from the 2010 national survey on drug use and health: summary of national findings, vol NSDUH, Series H-41, HHS Publication No. (SMA) 11-4658. Substance Abuse and Mental Health Services Administration, Rockville, 2011 Effects on overall functioning and future substance use

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